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The Wingham Advance-Times, 1983-03-30, Page 41Executive members of the Goderich Branch of the Canadian Cancer Society are, left to right, Zella Crawford, commemoration; Fordyce, Clark, transportation and Olive Knisley, service to patients. Absent for photo were Angus MacLennan, president, Robert McCall, vice-president, Marj Brown, secretary, Eugene Bender, treasurer, Grace Hunter, planning, development and nomination, Hazel McCreath, publicity and Phyllis Pitblado, mastectomy visiting. (Photo by Joanne Buchanan) The Pap Test: It's simple yet important The uterus, or womb, is a small, pear-shaped organ located m a woman's pelvis. It has two parts; the uterus itself, and the neck of the uterus, or the cervix. The test for changes in the cervix or neck of the womb which can tell if a pre- cancerous or cancerous con- dition exists is known as the `Pr`st' or the 'Pap smear'. It is now part of the standard gynecological ex- am. This simple yet very im- portant test is painless and can be carried out in your doctor's office in a matter of minutes. If you are- sexually active or are over 18 years of age, discuss with your doctor how often you should have the test, since this May vary according to age and certain other risk factors. However, it should be done regularly. HOW IS IT DONE? Cells are gently taken from the surface of the cer- vix and placed on a glass slide which is sent to a laboratory. The cells are then examined under a microscope. In most women, these cells are absolutely normal. In a very few - about 6 out of every thousand - the cells do not look normal. When this occurs the test is repeated and, if necessary, further examinations made. THEN WHAT? Even if further investiga- tion or treatment is re- quired, the Pap test enables doctors to discover cancer, or pre -cancerous changes, early so that the chances for a complete cure are greatly increased. If any abnormali- ty is found, some additional procedures may be done by your doctor. A very common diagnostic procedure is a biopsy, where a small piece of tissue is removed and examined under a microscope. In a "cone -biopsy," the doctor removes a cone-shaped piece of the cervix which may not only be helpful in diagnosis, but also as treat-.. ment. Another simple diagnostic procedure is a "colposcopy," which is done in much the same way as a Pap test. The doctor uses a special microscope to ex- amine the tissues of the cer- vix and vagina. If abnormal cells are found, one simple treatment is "cryotherapy," a pro- cedure which `freeze -burns' away the abnormal cells and is often done in a special clinic. It is unlikely to have any effect on a woman's fer- tility or future child bearing. Another simple treatment is "laser cautery," where a very fine, precise beam of focused light vaporizes pre- cancerous cells on the cervix or vagina. GOOD ADVICE If you are told that your test is normal, you will naturally feel very happy. Remember though that the preservation of good health requires that the test should be repeated regularly. You should also remain alert to any unusual symptoms such as spotting after intercourse, or bleeding after the menopause. You should see your doctor at the first sign of anything abnormal. Keep in mind that though the Pap test is very successful in detecting cervical cancer, which is found in the neck of the womb, it isn't as effec- tive in detecting the other major form of uterine - cancer, endometrial cancer. This is a type of cancer found in the lining of the uterus which . is called the en- dometrium. Here, the repor- ting of any abnormality and regular gynecological ex- ams will help in the early detection and treatment. HAS THE PAP - TEST HELPED? The mortality rate from cancer of the cervix was generally on the increase un- til the early 1950's. That's when the Pap test was in- troduced to Canadians on a large scale by the Canadian Cancer Society. Since then there has been a significant decline in the death rate from cervical cancer. One of the most important reasons is early treatment as a result of the Pap test. To..ay's cancer research... ® from page 8 surgery, radiation and drugs (chemotherapy). Canadian researchers have made an outstanding contribution to cancer treatment by the development of the Cobalt bomb (an instrument used to radiate and destroy cancer cells). Radiation works best to destroy cells when they have ample access to ox- ygen. Unfortunately, central parts of tumors often have limited access to oxygen and maybe less affected by radation. Now being studied are certain chemicals called radiation sensitizers which are able to penetrate the center of tumors and substitute for oxygen, thus increasing the effect of radiation. Concentrating radiation on the tumor and sparing sur- rounding normal cells is a primary goal in radiation therapy. A new facility at the University of British Colum- bia called TRIUMF, Tri - University Meson Facility, generates subatomic par- ticles called pi -mesons. Pi- mesons can deposit energy (radiation) deep inside the body, striking a tumor with minimal damage to the nor- mal cells surrounding it and along the directed path of the pi -mesons. This facility is one of the only three in the world. The preliminary studies are nearly finished and after further research, it is expected that the ex- perimental treatment of pa- tients will begin. Tumors may spread to other locations by cancer cells breaking away from the main tumor and migrating to other parts of the body. Chemotherapy of- fers one method for the treatment of widely spread cancer. Chemical coin pounds are introduced into the body and find their way into most of the body tissues. These drugs are chosen and used in a manner planned to be more destructive of cancer cells than normal cells. Canadian scientists contributed to the develop- ment of a drug called Vin- caleukablastin (VLB) which is one of the few drugs which have been successfully used to treat cancer. New drugs are constantly being developed. Their method of action and usefulness in treatment of cancer are im- portant parts of cancer research. The study of genes In recent years, many scientists have also been stu- dying the genetic make-up of cells in relation to cancer. Endometrial cancer is curable The middle years are the time in a woman's life when she becomes increasingly vulnerable to cancer of the endometrium, or en- dometrial cancer. Briefly, cancer is a disease in which abnormal cells in some organ or tissue grow out of control and increase in number. They replace or destroy the normal tissues around them and may spread to distant organs. In endometrial cancer, the ab- normal cells originate in the endometrium or lining of the womb. Fortunately, endometrial cancer is curable, if detected early. There are two ways in which you can protect yourself against this disease. Learn to recognize the early warning signs your body may give you and, most im- portantly, insist on having regular gynecological ex- aminations. Sometimes, the signs of endometrial cancer can be confused with the effects of menopause, the time when menstruation normally stops. Menopause usually oc- curs between the ages of 40 and 50. Periods may become gradually shorter and fur- ther apart or they may stop abruptly. There should be no irregular bleeding between periods. Once you have gone for a full year without a period, you will know that menopause has occurred. After that, there should never again be any vaginal bleeding. If you experience irregular bleeding before or during the menopause, or any bleeding at all after the menopause, it is a sign that you should consult your physician immediately. There is a good chance that this may be caused by something other than cancer, such as uterine fibroids — benign growths in the wall of the womb — but it could be endometrial cancer. In either case, early treatment will benefit your overall health and well- being. Of course, some women develop endometrial cancer without showing any symp- toms at all. This is why regular gynecological ex- aminations are vital. If en- dometrial cancer is suspected, your doctor may perform an aspiration curet- tage. This is a painless pro- cess which can be done in the doctor's office. A suction device is used to remove sample tissues from your womb for microscopic ex- amination. In some cases your doctor may suggest Turn to page 10 • These studies of genes in- clude not only the study of in- heritance and hereditary factors, but also new techni- ques of genetic engineering. These new techniques allow the isolation of human genes for manipulation and study. For example, human genes for insulin and human growth hormone have been transferred to bacteria, in order to produce large quan- tities of human hormones for our needs. Genes for in- terferon are being manipulated by similar means and should, in the future, result in the produc- tion of sufficient human in- terferon for detailed testing. More general research is be- ing performed to identify genes and changes in genes which may result in cancer. Summary Thus cancer research pro- ceeds on a broad front — epidemiology, the detection of cancer related factors in the environment, and laboratory research into Poll* 9 these factors and others which affect the prevention, detection and treatment of cancer. No area operates isolated from the other. Together they co-operate to provide an understanding of how cancer occurs, how to prevent such cancers in the future and how to successful- ly detect and treat those which already exist or do oc- cur. The research required for the challenge of eliminating cancer is expen- sive. The Canadian Cancer Society is the major source of funds for cancer research in Canada. Recently the Terry Fox Marathon of Hope has added a new dimension to cancer research by enabl- ing even more projects to be funded. The volunteers of the Canadian Cancer Society, the doctors who treat cancer and the researchers from the sciences of epidemiology, physics, chemistry and biology continue to co- operate in the march towards solving the pro- blems of cancer. 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