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The Brussels Post, 1894-8-17, Page 71 TUNRCULIOSTS IN CATTLE, CENTRAL EXPERIMENTAL FARM BULLETIN, NO. 20, Tuberculosis In Callao and Consumption !n the llumtut Faultily Aro One and the dame T*i g. -+Monies of Attack—Tae l►ingeosfs or the Disease—Experience 1n Cauuda,' Tho Department of Agriculture has just issued Bulletin No, 20, of the Central Ex- perlinontel Farm, Ottawa, dealing with tuberoulosia. It begins by elating that tuberculosis fn cattle and eoneumptioa in the human family are one and the same thing. It is a disease entirely distinct from pleuropneumonia, and occurs in cattle wherever they are kept in domostication. All animals, even to fowls, are More or less subjectto it. It has long been known that tubercle •contained virus or poison which if injected into the tissues of animals was capable of produoing tuberoulosia, but the exact nature of this material was unknown until 1882, when Profeesor Hoohof Germany announced his discovery of the germ of tuberoulosia, a bacillus known as bacillus tuberculosis, which is now admitted by all scientific in. vostigators.to be the sole otuse of this disease, This gorm is a vegetable parasitic, micro-organism which, under high magni- fying power, appears as afine rod,often alightly bent or curved, about one-tenth as broad as long, and measuring about one t sWhen even thousandth th of an inch in length. �V u d g this baoillue finds lodgment in an animal under favorable conditions it multiplies with great rapidity. Within this minute organismP gsmall oval spores are formed which are feat liberated and develop int o mature forms like the parent. As a result of the multiplication of these bacilli in any of the internal organs small nada ler bodies aro formed called tubercles, These in their early stages are about the size of a millet goad, but soon increase in number and size, and uniting form larger diseased masses, As these grow older a process of suppuration takes place, the �££ tubercle becomes yellow, gradually softens E and forme a cheesy mass. This mass of ohoese•like consistence may eoftei stilt more and become of the consistency of ffl cream, or from the deposition of linie salts in it, the masa may become quite hard. When present in any quantity in the inter- ior of saoh organs as the lung or liver, tubercle is most frequently soft, or fluid, forming what is known as a tubercular abscess. but whore the disease affects the surface of an organ, or attacks a mom - bran the growth is usually harder and nodular. Those tubercles or portions of tubercle near the surface of a diaaaeed area contain the largest number of active bacilli and these are thus in a favorable position to invade the surrounding healthy tissue, or to be carried by the circulation to other parts of the body and begin there the for- mation of further tuberculous masses, mODIt8 OE ATTACK. The bacillus of tuberculosis may enter the body and bring on this disease of the animal by being taken with the air into the lungs, by being swallowed with food and thus introduced into the digestive system, or iu rare cases by the accidental application of disease germs to outs, wounds or other excoriated surfaces. Onceintroduced into the system the dis- ease may become general or may only devel- op locally, by attacking a single organ. In some instances its action is very rapid producing what is known as " galloping ootsumption." In cattle the lungs, the glands in the thorax, the pleura and the siriue membranae which covers the walls of the thorax and abdomen, are the parts most usually a60cted by the disease. The glands iu the chest, behind the lungs, aro very commonly diseased and often much enlarged. The tubercle baoillue is contained in very large numbers in the matter expectorated by individuals suffering from this disease, also by cows who are sued t0 discharge this material through the nasal organs, and these bacilli remain actively virulent for a very long time, Experiments have been tried by drying such expootorated matter for many months, and also by alternately wetting awl drying the material; the bacilli. have also been exposed for a considerable time to cold, as low as 18 degrees of frosts. and to temperatures as high as 10S°F. with- out affecting their vitality. When animals have been inoculated with material so treated, the bacilli have shown unimpaired vigor, and have rapidly brought about diseased conditions. It is evident then that such disohargee when allowed to dry, or in the stalls or sheds of animals suffering from the disease, h000810 a source of danger to all about them, both men and animals No reliable remedy has yet been discov- ered for this dieees°, and the only way known of freeing a herd of cattle from it is by the prompt destruction of all affected animals. Frons the absence of outward symptoms the detection of tuberculosis in its early stages by the ordinary methods of examination is very difficult, and in many oases practically impossible, and by the time the disease has progressed far enough to be readily detected there ie danger that the affected animal has already conveyed ib to others. A cow attached by tubercul- osis may die in a few weeks, or may live for many months, and sometimes for sever. al years. The percentage of milking ani- mals affected is usually greatest in the neighborhood of cities where they are housed for the greater part of the year. Hence the importance of sanitary measures such as proper ventilation, pure water sup- ply, adequate disinfection of stalls where tuuarciloue animals have been kept, and prompt isolation of all euspeoted oases. THE DIAQNOS38 OF TI1I5 DISEASE, by ordinary means being in many oases all most impossible, a more trustworthy method has been sought, and found in Kooh lymph or tuberculin.. This is prepared by first malting an artificial culture of the disease germ known as the bacillus of tuberoulosia and allowing ittostand until the material has become highly charged with the bacilli, A proportion of glycerine is added with a little carbolic amid. It is then filtered through porous porcelain to separate the germs and the filtered fluid raised to a tem- poraturo high °bough to destroy any re. inaining germs which may be fn tho fluid. 70 degrees Centigrade equal to 158 0 of Fahrenheit. is about the temperature used ' for this purpose. An exposure of ten min uteri to such heat is said to destroy all traces .of vitality ,in these germs, Tho sterilised fluid is next evaporated at a low temperature in a vacuum until it to aufli- olenIly concentrated when it is put up in AMU betties each containing vide hie centimeters opal to aboub 80 minima, and uesafly sold In New York at about 310 sash. To prepare this fluid for neo it is diluted with mull disco its volume of a ono per cent solution of carbolic acid in pure water. When a email quantity of this diluted tuberoulous iolnjeotad under thoskln of a tuberoulous animal the temperature of the body risosoonsiderably, while in animals free from this disease no such o9'egt is pro. duffed. Tho dee in temperature does not. take place immediately, but occurs ab dii. femme periods from 3 to 20 hours after the nj cation has been made. ExrnuisNCE IN ()ASADA. Canadian cattle as a rule are remarkably healthy, especially such herds as are kept lite greater part of the rims in the open air, a result no doubt due to the invigorating and health -giving eharaoter 01 the Canadian climate. It has, nevertheless' been long known that tuberculosis existsto a certain extent in different parts of Canada among cattle kept thegreater part of tho year in oonfinment, or when oloeely bred. Prior eo 1888 the eubjaet was much discussed, and during the mission of the House of Commons in that year a sub -committee was appointed for the purpose of considering the question of certain contagious diseases in cattle and their communicability to man and animals with spacialreferenoe to tuber- culosis, Tho committee presented a report to the House in April, 1889, in which much useful information fa gtvon regarding this disease and the means by whioh it is spread. After a cevidence areful consideration of all the which the committee had obtained from physiolans and veterinary surgeons iu differentparte of the Damlr,ion, tilomembere expressed the opinion that the disease known as tuberculosis then existed among cattle in Canada to a much greater extent than was generally recognized. In this report reference was made to the oontagions character of the disease, that it was always due solely to the presence of the tubercle bacilli, and to the fact of its being communi- cable from animals to man. The committee also recommended that the milk obtained from all suspected animals should be boiled before using, and that the meat where used should be thoroughly cooked so as to des- troy any bacilli which might be present. CHEAPER HARVESTING. Everylaring Entering Into the Cost or liar vesting Inas Been Materially Reduced This Year. The cost of taking off our grain crop should be a good deal less this summer than it has averaged in recent years. Several causes combined to make a substantial say ing in the mouoy cost of harvesting. In every harvest a largo percentage of the machinery, tools, and fittings used is new. The total outlay necessary on this renewal account has been materially out down this year. In the first place the duty on agri- cultural implements and machinery is now 20 per sent., whereas last year it was. 35 per sent. if the ditferenoehetween foreign and domestic prices amounts to the whole duty, then the lower tariff means a saving of above 11 per mint, in the cost of the femora' implements. But a still greater element in the diminution of the price is the decline both in cost of PRODUCTION AND IN PROFIT, The extremities to which depression has brought industry and capital in the United States is the cause of this. From the time production begins at the mines until the moment the fiuished implement is put down at the border, there is a constant saving of expenses, by means of fewer hands, lower wages, and cheaper methods, which the pressure of hard times and of competition enforces. Iron ore, pig iron, finished iron, steel, and all other materiel, are aaoh pro- duced at some economy of cost, and the aggregate of these economies makes a heavy disoounton the former prices of implements Freights have been worn down by the same friotion of dull business and keen competi- tion. Further, manufacturers are satisfied with lower profits in these hard times, Consequently, harvest and other agricultur- al implements are offered by United Stenos manufacturers tab a much lower price than they ever were before. It is in such times that the merits of an ad valorem duty aro appreciated by buyers. Twenty per oent. of the present low price of a United States binder is a good deal less than twenty per cent. of what the price was two years ago. Of course our manufacturers have to meet the low prices whish those of the !United States are quoting. The farmer gets the benefit of the lower duty, the lower cost of produotion,and the lowerprofit,which must mean a large savine. In binder twine there is also a groat change forth° bettor. Hegets that for nN a.TuIRD TO ONE-IIALP LESS than he used to pay for it. Last year bile duty w05 lowered ogle -half, twine mahtag was begun in the central prison and this year itis begun iu the Kingston peniten• tiary, while some time ago the Patrons of Industry opened a faotory. With lower duty, Dominion and Provincial convict labor, the co-operative principle, and competition all at work to produce cheap twine, there was little ohanae for the sur- vival of exorbitant profits. Labor oleo should be obtainable at reasonable wages. In the towns and cities there is just Dow a surplus of able-bodied min who should be glad of a few weeks' harvesting. All the staple aruticloe of consnmption, which the farmer has to buy, are remarkably law prised. Sugar, tea, and like commodities were never before so cheap. Everything considored, the farmers ought to be able to get through their lar. vesting for less money than they ever did Mime labor-saving machinery tante into general use. There never was a time when relief from expense was more appreciated as there never was a time the farmer got so little for his grain. A Specimen Prediction. Weather Prophet—"I hit it again. I never fail." Ordinary Man, —"Huh 1 Thetheremom• °tar has dropped twenty degrees, and itis raining pitchforks. You predicted fair and warmer." Weather Prophet—" I prodioted fair and warmer, with increased humidity. I may have boon -a trifle off 'on the fair and worm- er, but you can't deny the humidity, air —no, sir." ,. One of the Etat Indian Sultnite is a dwarf only 3 feet 10 mehes, but his name is one giant word of 59 lettere. •B °F5' ELECTRIC BICYCLE LAMPS, The Current for Otne Generated by the 3Whe01e. George Mayr, of Brooklyn, has invented a lamp for bicycles, the power for which is prorated from the wheels. The invention, the application of which is shown in the illustration, which is self-evident and de. mends no particular deeot'iption, consists in the eombination with a bicycle having a prop kat wheel mounted on a )tub of one of its wheels, a dynamo.elootrio generator of, speoial design, °aitably dl°pooed upon the bioyole frame, and consisting in part of a gearing framepieoe, a horizontal armatu re shaft carrying a pinion, and a train of THE DYNAMO BIOYCRE. gearing mechanism, disposed in the frame- teoe the initial drive of the gearing frame- place, it'nism being carried by a shaft havin a sprocket wheel mounted upon it and the nal driver thereof fi v f bait, adapted to mesh at all times wibh the pinion on the armature shaft; an electric lamp of any approved aonatruction, mounted on the bioyole frame, and circuit cone:tion leading from the generator to the lamp. Another lamp consists of battery and headlight complete in one aompaot case, • RCN BY:sTORACE. and resembles in appearance an ordioary oil lamp. The battery is an improved form of secondary cell, and posseeses the advan- tage of containing no liquid. This battery may be charged by primary eells or oonneo• tion may be made with an electric eirouit used for lighting purposes. Tbis style of lamp is intended to use upon bicycles, but modifications of it exist which may be used by miners, policemen and those who need a bright light fur frequent use. Sanding a Message Round the World. One day lash April a telegram was put into the hands of the courteous ;thief engi- neer of the British Postal Service, Mr. W. H. Preece, with the request that he would say whether it could bo sent round the world by a certain route, and if so what it would oast per word. When the writer of this article went a feu' days later to look after the progress of the telegram, Mr. Preece shook his head. "The whole foreign Department are at it," he said, "and they are tearing their hair and pro- testing, but you shall haveit soon." The route planned was rather erratic. It asked that the message bo sent by a cir- cuit whish would take in the entire tele graphic field of the world, touching at'the moot remote points, but never leaving the land line or the oable ; that is never being transferred by post or messenger from one point to another. Starting at San Francisco, the route ran across the continent to Now York by Vancouver and Montreal. From New York it followed the world's northern telegraphic boundaries through England, Norway, Sweden, Russia and Siberia Going south, it touohed at Nagasaki as Japan, Hong Kong in China, Singapore, lava and Sumatra, crossed Australia and landed in New Zealand. Returning to Singapore, it crossed to Bombay, made a detour to Coy- lon, then on to Aden, rounded the Cape of Good Hope, leaving the line at Zanzibar to call at Seychelles and Mauritius, amounted the West African coast to St. Louis in Sen- egal, crossed the South Atlantic to Pernam• Mum, traversed South America fronf'Buonos ,lyres to Valparaiso, and than went north through Mexico to New York. In a few days, true to his promise, Mr. Preece had the answer ready. The telegram could be sent. It would require about nfby-nix hours, and would cost about 90 francs (01S) per word. TO GERtMANIZE TH-E DUTCH. A I'0saltll0 Note or liar. The destiny of little States is to be ab- sorbed sooner or later by some powerful neighbor. For Holland that neighbor is Germany. Holland has vast colonies whish enriched her in tunes past and made her oommer0e flourish. But the colonies now are deer luxuries for the mother mut- tor, and are far from being profitable. This would not be the case, naturally, if these oolonies belonged to mighty Germany. But there is another reason for theabsorp• tion. In the coming great war Belgium and Holland will be the apple of discord between Franco and ('Germany. Franco will capture Belgium, and Holland, too, if Ger- many does not take good one. Historically, Holland is of German origin. She formed part, up to 1648, of the "Carole de Bourgogne," Her language, intellectual life, the history of her dynasty and its branches in the reigning German families' all go to assign Holland to Germany. Tho Hollanders aro more German than they want to admit. Joan Paul was right when he called then!" a ahoapediton of Germans upon ordinary paper and without engrav- ings." Ab the present time the Dutch aro oppos- ed ro annexation; but there is a way to got rid of their opposition. Lot a German Prince become the husband of the young Queen. That Prince should be the heir to the throne of Gerumny. In this way he would in timobecoma Emperor of Germany, Xing of Prueeia, and King of Holland. Some of the wolfs in Polk County Nyb ebb wad flow lfko the tidos. CHINA'S PLAGUE AND LONDON'S, Who IUseasc Relieved 00 be the Seine, anl. to be Mani by With. Tice plagne raging in China, X10 ie now said, fo identical with the epidemic kuown in history as the Great Plague of London Tho plague first appeared in London late nthe autumn of 1004. It was quiescent during the following winter and early ppriug, but in May broke out again in the parishes of. St, Giles and St, Martin, in what woe then the extreme west end of the town. It took the epidemic oix months to resell the extreme east end, butitsprogress, if slew was sure, and tens of thousands of people perished, The disease increased steadily in violence in tin °puss of the summer, and was at its height in Septem- ber, when more than a thousand persons a day died. From that tremendous total the deathrate fell to almost nothing in October. The figures for the five months in whish the plague was epidemic are; May, 43; June, 690; .luly, 6,137• August, 17,036; Septem- ber, 31,169. Thisamakes a total of 68,590 deaths in a population of 460,000. The total is believed to be too low, for of the 6,432 deaths in that tine of spotted fever many were doubtless due to plagueand were reported differently to avoid the difficulties thrown in the way of the funeral and burial of victims of the plague. Some plane the plague mortality at 100,000. Long before tite pestilence had reached its height, London had been deserted by two.thirds of its inhabitants. Those who remained were the poor who couldn't eta a From the first the had been g wy. Y the ohief victims of the pestilence which was called the poor's plague. They were probably scourged by the pestilence, not because they were poor, but because they were dirty. London at that time was as dirty. end in as bad sanitary condition as the cities of the East, which the plague seldom leaves, are in now, and the poor lived in its dirtiest quarters. Bro horst ,a contemporary ph sioian, attr;buted the pestilence to the local causes of filth, un- cleanly habits, and surroundings, and bad sanitary arrangements. His explanation of the great plague has been Accepted as the true one, and to thesecauses the plague in China is due. In Hong Kong today as in London in 1665, persons of cleanly habits may expose themselves to contagion without fear. Less than a dozen physicians died during the Lonlon plague, and overfatigue and ex. haustion probably hastened their death. A favorite praotiae in London was to lock up a house containing plague patients and mark it with a red cross accompanied by the inscription : "God have mercy on us," to warn outsiders. The; result was that everyone in the house died, as a rule, while the premises remained a breading place of pestilence. The plague spread widely in England, but nowhere was so severe as in London. In Oxford, whish was noted for its clesu con- dition, the pestilence made no progress e,t all, notwithstanding its nearness to London. The plague revived in London in the spring of 1666, but only 2,000 deaths ro• suited, and the pestilence was well under control long before the great fire, which is popularly supposed to have swept it out of existence. Defoe wrote what purports to be an account of the plague, which is equally realistic' and thrilling, but there is reason to believe that it is more interesting than trustworthy. THE APPENDICITIS FAD. Popular Errors About Grape Seeds Exploit ed by a Prominent Surgeon. A prominent doctor who has performed a score of successful operations for the re- moval of that troublesome and inexplicable part of the human anatomy, the veriform appendix, says that the general impress- ion that appendicitis is caused by the presence in the appendix of a cherry stone or a current seed or a seed of any kin.i is entirely erroneous. " I have not found a seed in the appendix of a single one of my oases," he said• " A small bit of digested matter gets into the little sac, if the neck of ib is opon far enough to receive it. It may remain there for years and pause no trouble, and then again it may bring on appendicitis almost immediately. Where the patient is m good health, in four oases out of five the operation for removing the appendix is successful. There is a great difference in the length of time taken by surgeons to perform this or, iu fact, any 11elicete operation. There is one surgeon whe has performed the operation in sigh• teen minutes, which included the time from the moment the patient was brought in oil the operating table until be was ready to be taken out. Ibis is half the time that, it requires the majority of skilful Burgeons to do it. Of course speed is not evel'y- , The appendicitis fad, as the craze among riot people to hove their vermiform appendices removed is called, still cou- tinuea unabated, and there are few 'surgeons of prominence now who are not familiar with the performance of the operation. A story is told of a doctor who is constantly ordering the removal of the vermiform ap- pendix for patients. He was called to sac a gentleman one evening who had been rather seriously injured. The gsntlemau, when he recognized the doctor, said: Oh, itis you; then 1 must have ap' pendioitie ' Doctors who have allowed the appen• dioibis fad to carry them away have per- formed the operation upon a great many people whose vermiform appendices were in good condition, and In some cases pa. bents having weak constitutions have diets because of the needless slit in their ab- domens, I aro very glad to explode that story about the grape seeds and other seeds especially as the grape season ie just com- ing on. People who have heard about appendicitis have given up the luxury of small fruit in fear of appendicitis, and some of the extremely sensitive ones have even loon constantly worried lest some send that they had swallowed, in the past might give diem this dieeaso—which is among el, rar- est of diseases, auytvsy." Dwelling. First Executioner—I hoar that you've eft your old prison 1 Second Exoontioner—Yes. First Exstotioner—Well where do you hang out now '3 Impossible Conditions. Housekeeper -"I'll give you all you want to eat if you'll tank down this carped' Tramp—"Couldn't, mum. If you'd give me all I want to cat, I'd have to stand up, 7 THE CHIGNECTO MARINE RAILWAY Au I;xtcnsten ornate Asko1) ror tno Cola* tkletlan el 01(0 Works, Mr, A, D, Provand the representative of the Blaokfriars district of Glasgow In the Imperial Homo of Ominous, arrived in Ottawa the other day for the purpose of in, terviewing the Government and urging on behalf of the British ebareholdora of the Cliigneoto marine transport railway that an extension of time be granted forthe con. pietion of the works. As is generally known, the railway is located iu Cumber. and county, N. S., and is designed to ob. viate a ureat detour around the Nova Sootia peninsula for vessels, by carrying them overland from the straits of Northumber. laud to the Bay of Fundy, or vioe versa, a distance of 13 miles. Several years ago the Dominion Parliament voted n subsidy of a quarter of a milltou dollars annually for 20 years to this enterprise, provided that the railway was actually in operation dur- ing that period. Uutil the road was emu. ally running not a Dent of subsidy was to be paid. The time in which the subsidy oould be earned expired long ago, end the promoters have received frequent 000000• aiona in the matter of extensions. Whether- the present application will be entertained relnaloe to be seen, but the feeling is pre. valent in official oiroles than the concern has so far been dealt with Very leniently. On Monday Mr. Provand, accompanied by Mr. H. G. C. Ketchum, of Amherst, the engineer who has built the worke, ono Mr. Dickey, M. P., hod au interview with Mr. Bowen on the subject. Mr. Provand de. w � v tailed the ciroumetancosin which the under- taking now stands. lie stated that an English firm of contractors, Messrs. Pear- son ft Sona had seat an engineer to report on the state of the works and they wore willing to assume the °entreat for rho com- pletion of the railway, work remaining tope done consisting prinoipally of the entrances to the canal andg uttin in the hydraulic p ner ma lifor liftingthe vessels. The machinery necessary money has been raised, and the promoters are willing to go ahead, provided an extension of time be granted. Hon, Mr. Bowel! said that he would lay the matter before his colleagues. An elevated railwaywith novel features is planned for ViennThe carmine to be suspended instead of runningupon ordinary ed i p rails. Found Saxon Coins, A man working the other day at the foundation of a houoe which 30 being erect- ed in Derby road, Douglas, Isle of Mau,. unearthed a stone receptaeie oonbaining large .quantity of coins, ringa, and bangles. Ti;e men, being short-sighted, did net ob. serve what his find was until soma of the bystanders seised some of the coins and ornaments and appropriated them. He then took possession of as many as he could, nearly a shovelful. They were apparently all of silver. The spot where bhey were found 1s about six yards from bho high road, and about one foot below the surface. The coins are silverskeatta or pennies, the common Saxon coinage. Such as have been examined proved to be of the period A.D. 925.965—that is a century later than Al- fred. They belong to the reigns of A 0801. 00,81 (A, D, 925), Hired (A. D. 948), Ditty (A. D• 955), and Edgar, the first king of all Englond(A. D. 959). One example of Atbelstan has the legend " Ellelstan re to Brit' Another specimen has the legend " Iiladgar re Angler." and another of tine same monarob hae the legend very distinct, " Badger re." The coins were, of course, much corroded. 'Blood Poisoning Mrs. 5iary E. O'Fallon, a very intelligent lady of Piqua, Ohio, was poisoned while assisting Physicians atm autopsy o yam's ago, and soon terrible ulcers broke out onher head arms tongue and throat. Her hair all came out. Her husband spentltundreds. of dollars without any benefit, bho weighed but 78 pounds, and saw uo prospect of help. At last she began to take hood's Sarsaparilla and at once improved; come soon get out of bed and walk. She says, "1 became perfectly cured by POrs. 8,7.38.O'ranon. Hood's Sarsaparilla anti Mn now a well woman. I weigh 123 hounds, eat well and do the work for a large family. DIy case seems a wanderful recovery and physicians look t t e in astonishment, I bi n n laeted.. as almost lake One rn ised frons fisc deed?' HOOD'S PILLS should be in every iamily medlclne 11.e^t. Once used. always preferred. ysterilysteries the The latest discovery in the scienti- fic world is that nerve centres located in or near the base of the brain con- trol all the organs of the body, and when these nerve centres are deranged the organs which they supply with nerve fluid, or nerve force, are also deranged: When it is remembered that a serious injury to the spinal cord will cause paralysis of the body below the injured point, because the nerve force is prevented by the injury from reaching the para- lyzed portion, it will be understood how the derangement of the nerve centres will cause the derangement of the various organs which they supply with nerve force; that is, when a nerve centro is deranged or in any way diseased it is impossible for it to supply the same quantity of nerve forco as when in a healthful condi- tion ; hence the organs which depend upon it for nerve foals suffer, and are unable to properly porfbrm their work, and as a result disease makes its appearance, At least two-thirds of our chronic diseases and ailments are Sue t0 the imperfect action of the nerve centres { at the base of the brain, and not from Ss derangement primarily originating in the organ itself. The great mis- take of physicians in treating these Siseaees is that they treat the organs and not the nerve dankest which are the cause of the trouble. The wonderful eures 'wrought by the Great South American Nervine Tonic are due alone to the fact that this remedy is based upon the fore- going principle, It cures by rebuild- ing and strengthening the nerve centres, and thereby increasing the supply of nerve force or nervous energy. This remedy has been found of infinite value for the cure of Nervous- ness, Nervous Prostration, Nervous Paroxysms, Sleeplessness, Forgetful,. nese, Mental Despondency, Nervous. nese of Females, Hot Slashes, Sick Headache, Heart Disease, .The first bottle will convince anyone that e euro is certain. South American Nervine is with. out doubt the greatest remedy ever discovered for the cure of Indigestion, Dyspepsia, and all Chronic Stomach Troubles, because it sets through the nerves. It gives relief in one day, and absolutely effects a permanent cure in every instance, Do not allow your prejudices, or the preju• dices of others, to keep you from using this health.giving remedy. 10 is based on the result of years ori scientific research and study. ,!t Bingle bottle will convince the most incredulous. A. IDk:ADALAY Whologalo and ROtail AgCltt for 1Rt'nsSels