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The Rural Voice, 1988-07, Page 20worms are free-living in the soil and enter the insects through natural openings. Once inside, they mature, multiply, and reproduce more "immatures" which leave the insect for the soil again. The bacterial infection caused by the nematodes kills the insect. The nematodes have shown some effectiveness against cutworms in lab and greenhouse studies, Dr. Morris says, but have not yet been effective in field trials. An entirely different form of bio- logical control attempts to use a pest's own chemicals to kill it or to disrupt the life cycle enough that the popula- tion will fall. The chemicals, princi- pally hormones and pheromones, have been synthesized artifically for some time and were thought to be good can- didates for controlling insects. They were completely specific for the target species and ineffective against any- thing else. But they have not proven very practical. Pheromones are now used almost exclusively as monitoring agents, and the big hormonal hope of the 1960s, juvenile hormone, is pretty well finished as a control agent, according to Dr. Robert Bodnaryk, an insect biochemist at the Agriculture Canada Research Station in Winnipeg. Dr. Bodnaryk says that an inter- esting prospect for hormonal control involves prothoracic tropic hormone (PTTH), which is made in the insect brain and affects the production of other hormones responsible for as- pects of moulting. New technological developments in Japan have meant that enough PTTH has been isolated to allow the structure to be worked out. It is hoped that through genetic engi- neering plants can be convinced to make PTTH, so that when an insect eats the leaves it will get a dose of hormone and die. This manipulation of plants, either by breeding resistant varieties or by using genetic engineering, is enjoying a high profile in biological control. Resistant plants are not new. The wheat stem sawfiy, for example, was controlled in the early part of this century by breeding a wheat variety that had a stem unsuitable for the insect. What is new is the range of possibilities brought to the field by genetic engineering. Now, by using gene splicing and viral vectoring agents, characteristics from one group of plants can theoretically be inserted into another unrelated group. Even non -plant material can be looked upon as potential plant material. For ex- ample, a great effort is being made to get the genes that produce the Bt toxin inserted into plants so that the plant itself will produce the toxin and protect itself from insect damage. Some of the methods of plant protection being considered by genetic engineers are nearly unbelievable. A British study is looking at whether Bt toxin genes can be inserted into an insect virus in order to make it more toxic to insects. Another British study is looking at whether a bacterium can be used to carry a fungicide to plant roots. An interesting aspect of this study is that the bacterium will only produce the fungicide when the plant is injured and most vulnerable to fungal infection. The bacteria con- gregate around the wounds and their combined numbers cause the produc- tion of the chemical. When the wound heals up, the bacteria disperse and stop producing the fungicide. It is evident from this brief outline of methods and ideas that biological control is a vibrant and thriving field. Yet, despite its advantages, biological control is not being used at the farm level. Biological control systems or disease sprays have not been devel- oped for the major agricultural pests in Canada. The reasons this is so are complex and diverse. Dr. Laing says there are three primary explanations. In the first place, it is difficult to make any money from biological control, so companies do not get involved. The problem for industry is that when a biological control method is perfected, it enters the public domain. Industry cannot patent the control organism or govern it in any other way to get a return on its investment. Dr. Laing says that it is the nature of biological control to be self-perpetuating and a public enterprise. This is both its beauty and its downfall, for without industrial involvement there is no promotion of the product. A second factor is that chemicals are largely successful, cheap, and effective. In spite of the long-term problems with chemicals, they have done their job, Dr. Laing says, so there has been no incentive to look for new techniques. The third factor relates to the first. Governments and universities are the main source of funds for biological control. There are only a few ento- mologists working in the field in Canada, and governments are reluctant to increase funding to such a low - profile area. Dr. Morris also points to econo- mics as the reason why microbial insecticides will never completely replace chemicals in agriculture. He says they are too specific for their target pests, making commercial production unprofitable. The cost of application is higher too. Dr. Morris thinks it will be a while before micro- bial insecticides will compete with chemicals even in terms of propor- tional use (i.e., a 50-50 split) but is optimistic that the problems will be worked out. On top of all these economic problems, there is the problem of public attitudes to the compounds and methods used. Despite the general desire for safer methods of pest control, Dr. Laing says the public has a funny perception of biological control, especially when it comes to pathogens. People hear of a virus being sprayed onto cabbage and panic, even though they have been eating that same virus (which is on the leaves from natural infections) for years. Dr. Laing speaks with some anger about an editorial in the Windsor Star recently (March 14, 1988) that criticizes the release of the parasite Trichogramma. The editorial worries that "history is full of examples of shortsighted experiments with nature that have backfired." It then goes on to use as examples the release of starlings to North America and rabbits in Australia. This editorial, Dr. Laing says, represents the public's general lack of understanding about biological con- trol. The writers failed to realize that Trichogramma is not an exotic para- site, but is native to Canada. Even if it had been an imported parasite, Dr. Laing says, insect parasites are biolo- gically tuned in to their hosts, and will live only in the target species or one closely related. He stresses that insect 18 THE RURAL VOICE