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The Rural Voice, 1999-03, Page 30Fighting fusarium Researchers stalk a solution to the costly problem of fusarium in corn By Ralph Pearce Fusarium. —One simple word — one devastating effect. Call it Fusarium head blight or ear mold, the term ,still causes producers and members of the agri-food sector to shudder. The most recent and devastating incidence of Fusarium occurred in 1996 and virtually wiped out the wheat crop in Southwestern Ontario. In corn. outbreaks in 1986 and 1987 largely affected the livestock industry. And the condition can occur to a lesser extent in any given year. But now, research is underway to eliminate Fusarium in corn. With the opening of an ethanol plant in Chatham (and another near Cornwall to begin production within five years) as well as expansions at two of Casco Inc.'s three corn processing plants in Ontario, it's arguable the need for research into Fusarium in corn ranks ahead of wheat. It's not that wheat isn't important to Ontario. But corn is also finding new customers for its products contributing to everything from snack foods to auto parts, building materials to soft - drinks and now pharmaceuticals. For Ken Hough, research co-ordinator with the Ontario Corn Producers' Association, the timing for finding a cure for Fusarium is now. Although outbreaks have been sporadic – and conditions for severe Fusarium infestation must be precise — the applications for this kind of research can be far-reaching. "In simplistic terms, we're looking at it (from) genetic resistance as opposed to the treatment of the symptoms," explained Hough, comparing it to the treatment of diabetes. He said researchers want to find a cure for Fusarium, not a treatment. Two phases of research have been initiated, the first in May 1997 and the second to begin in April -of this year. Phase One has dealt with gene isolation and transformation into the plant along' with establishing molecular markers – 26 THE RURAL VOICE also known as DNA fingerprinting. Phase Two, to take place over three years, will expand on those applications, including cloning and yield testing of transgenic lines. The Agricultural Adaptation Council has provided $310,000 (via the CanAdapt fund) to both phases and nine private companies, including Pioneer and Novartis, are involved as well. Hough indicated Canadian work on Fusarium is far ahead of U.S. research into the disease, where more money is spent on aflatoxin and fumonisin; conditions that are of greater concern south of the border. Here in Ontario, work _ is ongoing at both the University of Guelph and Agriculture and Agri -Food Canada's Eastern Cereals and Oilseeds Research Centre (ECORC) in Ottawa. Peter Pauls, from the Plant Agriculture Department at the University of Guelph, is involved in the development of a transformation system and work into identifying a DNA fingerprint for Fusarium resistance. In the development of a transformation system, a cross of plant traits has been created in which disease resistance can be determined through DNA screening. From there, the crosses were identified for varying degrees of resistance and are now in New Zealand to winter and grow seed. In the spring, they'll be returned for resistance testing in Ottawa. By the end of next summer, suggested Pauls, researchers will have an idea of which markers are linked' to disease resistance in corn. On the transformation side of the project, Pauls indicated there are two methods of transformation; via a particle "gun" (which shoots the DNA into a plant) and through tissue cultures. The challenge with tissue cultures is that corn — a monocotyledon plant — is not susceptible to agrobacteria; dicotyledons (like beans) are. The solution in this case is to use molecular markers —