The Rural Voice, 1990-12, Page 16can•con mill
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12 THE RURAL VOICE
DIAGNOSTICS
SIRS
"MYSTERY DISEASE"
by Dr. S. E. Sanford,
VETERINARY LABORATORY SERVICES
Swine Infertility Respiratory
Syndrome (SIRS) has been proposed
as a more accurate name to replace the
vague and potentially inflammatory
term "Mystery Disease" reported one
year ago in this column (December
1989, pg. 18).
Until the true cause of the disease
is known, SIRS brings into focus the
two major components of this
syndrome: (1) the reproductive
problems, and (2) the respiratory
distress.
To recap SIRS (formerly Mystery
Disease), several sows on a farm
suddenly develop fevers, go off feed
and abort, have stillborn piglets, or
farrow a few days early. These sows
also exhibit heavy breathing/
respiratory distress. The early -born
pigs are small, weak, and die or fail to
thrive especially if they develop any
of the secondary infections that
frequently follow.
SIRS Update: Actual SIRS outbreaks
in sow herds in the U.S. have been
much fewer over the last year, but the
respiratory distress and failure to
thrive have increased. In Ontario, the
outbreaks resembling SIRS that
occurred in 1987/88 have not been
seen during the past 1 to 2 years.
The search for the cause of SIRS
has continued and intensified in the
U.S. Most of this effort has been
directed at linking EMC
(encephalomyocarditis) virus with
SIRS. EMC virus does and is causing
abortions and stillbirths, and if pigs
survive after their hearts are damaged,
respiratory distress occurs.
However, EMC, although proven
present in many herds with SIRS,
cannot always be identified in herds
with SIRS. Furthermore EMC virus
can be demonstrated in many more
herds that have NEVER had SIRS
outbreaks than in herds with SIRS. So
the hunt continues for another agent or
agents, or other factors that may
combine with EMC to produce SIRS.
Most of the other agents that were
being investigated one year ago (eg.
Leptospira bratislava, Parvovirus,
influenza virus, chlamydia, etc.) are
no longer considered as being the
cause of SIRS.
THE QUEBEC SYNDROME: In
the meantime, a syndrome that may
have started out looking and sounding
like SIRS but now seems to be an
immunosuppressive syndrome, has
emerged in Quebec swine herds over
the past 18 to 24 months. This
immunosuppressive syndrome has
affected mainly grower/finisher pigs.
They develop a proliferative
pneumonia which may kill them or
leave them susceptible to several
secondary infections such as Strep
suis, Actinobacillus suis, and
Pneumocystis carinii pneumonia.
Pneumocystis carinii pneumonia is
one of the most common secondary
infections that occurs in people with
AIDS. Researchers in Quebec have
identified an influenza virus and are
investigating the possibility that it is
the cause of the immunosuppressive
syndrome.
A close watch is being kept in Ontario
to see if this disease occurs here. So
far one herd in the Guelph area has
been identified with similar lesions
and is being carefully investigated.
We have tried to keep our topics
timely and informative.
However, we would welcome
any suggestions from readers
for future topics. We would
also invite interested persons to
take a tour of the facilities at
the Diagnostic Laboratory at
Huron Park. We would ask that
you make prior arrangements
by phoning 228-6691, Ext. 276.