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The Rural Voice, 2001-06, Page 30After a long hard winter the heat is finally on. but that can be bad news for the effectiveness of your vaccines unless you take special precautions. Dr. Neil Anderson. veterinary science at OMAFRA. Fergus office and Tamara Keeley a research assistant at Guelph. studied the effect temperature could have on vaccines in storage on the farm and found proper storage can make the difference between an effective vaccine and one that is wasted. Both heating and freezing render vaccines useless and precautionary statements on labels emphasize critical temperatures for vaccine storage between 2-7 degrees C., Anderson told the Recent Developments in Pork conference in Shakespeare last winter. Freezing is a greater hazard for killed vaccines than modified virus vaccines. However. Anderson warned. several modified live virus vaccines use a killed component as a diluent. These combination vaccines must be handled as a killed vaccine. "Check the labels on most veterinary vaccines and you will find the same, or very similar 'precautions'. For simplicity, manufacturers of veterinary vaccines instruct us to handle all veterinary vaccines the same way." As part of their research, Anderson and Keeley looked both at the dependability of refrigerators and of coolers used for transporting vaccines. They recorded temperature cycles for four different 26 THE RURAL VOICE Cool it, man (and woman) It takes only a few minutes of too much warmth or too much cold to destroy the effectiveness of vaccines so keep them in a fridge or cooler By Keith Roulston 1 refrigerators: an office fridge, a house fridge, a lab fridge and a porch fridge (commonly known as a beer fridge). The refrigerators were 2, 19, 25 and 30 years old. Both shelf temperatures and temperatures on door shelves were recorded. What all the machines had in common was the cyclic fluctuation of temperature. The office, lab andporch refrigerators had a range of approximately three degrees from coldest to warmest. The house fridge had a range one degree colder on the shelf than on the door. On two of the fridges the shelf temperature actually fell below the freezing mark which would damage the vaccine. Within refrigerators the temperature can vary greatly depending on which shelf or where on the shelf, the vaccine is stored. Tests on the office fridge showed the back of the shelf remained below freezing for an entire day no matter what the cycle of the temperature. Cold spots are poor locations for vaccine storage, the researchers say. Anderson and Keeley also found the temperature could rise to 10 degrees C if the fridge door was kept open for 1.5 minutes. For that reason, they recommend vaccines not be kept in a refrigerator that's being opened frequently, such as one where lunches or drinks are stored. The researchers recommend making your refrigerator vaccine friendly by giving it a regular checkup. "Just because you hear it running doesn't mean it's working properly," Anderson said. Take the temperature inside the fridge several times over several days and keep records. Expect cyclic fluctuations in temperature. Overall your refrigerator must maintain a temperature of 2-7 degree C to protect you investment in vaccines. If it doesn't, call for service. If you take a vaccine or medicine out of the fridge. it can quickly warm up and lose its potency. Anderson and Keeley found. They tested how quickly 50 and 100 ml vials of water warmed up when taken from the fridge and left at room temperature. The 50 ml vial warmed to 10 degrees C in just 20 minutes and to room temperature in about an hour. The 100 ml vial warmed to 10 C in 35 minutes and room temperature in an hour and a half. While the researchers admit water samples may warm faster or slower than actual medicines, the lesson4 is to use medications promptly and return them to the refrigerator quickly, they say. "Our advice: learn from the coffee shop. Freshness counts," Anderson said. "At our local coffee shop, the time of brewing is written on each pot of coffee. If it's not sold within the "freshly brewed" time frame, the coffee goes down the sink drain. "This elegant coffee shop monitoring system should be tried for our vaccines," he said. "The next time you remove vaccine from your refrigerator, write the time on the medicine bottle. When it is empty, or returned to the refrigerator, note the elapsed time. Did you 1