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The Rural Voice, 1982-10, Page 32ANIMAL SCIENCE B.V.D. - Bovine Virus Diarrhoea BY Stan J. Alkemade, B.V.Sc., D.V.M., M.R.C.V.S. Bovine Virus Diarrhoea (B.V.D.) is a viral disease of world wide occurrance in beef and dairy cattle, characterised clas- sically by two syndromes. In the acute form of the disease young animals, generally twelve to twenty-four months of age, scour profusely, do not respond to treatment and subsequently die. A chro- nic form of the disease, often called Mucosal Disease, causes ulceration of the muzzle, tongue, pharynx and intestinal tract leading to a decreased food intake, poor food conversion, loose manure and loss of condition or milk production. During the last fifteen years, two and possibly three, new forms of the disease have been recognized. The virus is capable of crossing into the uterus and, during the first six to seven months of pregnancy, may cause infection and death of the developing calf, with subsequent resorp- tion, mummification or abortion. Some calves infected at the transition period of 6 - 7 months of pregnancy, may survive to be born hairless and/or with mild to severe nervous system disturbances. New- born calves can develop a B.V.D. viral infection in the first months of life leading to scours and death. Recent clinical observations in vaccinated herds in the U.S.A. and Canada indicate a possible link between the B.V.D. virus and calfhood pneumonia. Whether the virus actually causes lung infections or merely decreased the animal's resistance to other infectious micro organisms is an area for investigation. It is known that the B.V.D. virus can decrease an animal's normal immune responses and this may be the explanation. B.V.D. is normally spread from one animal to another by the ingestion of infected, fecal contaminated food or water. Additions to the herd of clinically normal, carrier animals is the common method of transmission between herds. Once the disease gains entrance to a herd most of the susceptible animals will become infected, show little or no clinical signs, and develop a strong immunity to OC ALFA -LAVAL and LENCO Dairy Supply Ltd. R.R. 1, Atwood 356-2282 ANNOUNCES: Mr. Jim Boak R.R. 5, Lucknow 357-1220 Sales and Service Jim is well qualified to serve you with the latest in dairy equipment as he was himself a dairy farmer and an ALFA -LAVAL user. Phone him and he will be glad to discuss your requirements with you. Pipe lines - Parlor - Bulk Milk Tanks - Plate Cooler - Energy Savers - Milk Meters - Water Conditioners - Water Bowls Ration Master Computerized Feeding Systems. PG. 32 THE RURAL VOICE OCTOBER 1982 the disease. Less than 10070 of the herd will develop the acute or chronic diar- rhoeic forms of the disease. Unfortu- nately, however, a larger proportion of females less than six to seven months pregnant may either abort or return to service. This is drastic in a beef herd but can also be devastating in a dairy operation. Vaccines for the prevention of B.V.D. have been commercially available for a number of years but their use has been questioned. New clinical and research data indicates that B.V.D. vaccination, in combination with other herd health preventative programs, has helped to reduce herd infertility problems as well as calfhood diarrhoea and pneumonias. A number of things should be con- sidered before a vaccination program is established. 1. Pregnant cows vaccinated during the first six to seven months of gestation may abort. 2. Calves which suckle colostrum from protected animals will not develop their own protection if vaccinated during the first two to three months of life. 3. Calves from cows vaccinated during the last two months of pregnancy will develop their own circulating protec- tion while still in the uterus. 4. Some animals are immunologically incompetent and will not develop circulating antibodies to the natural or modified vaccine virus. If a vaccination program against B.V.D. is to be incorporated into the normal herd health procedures, it can often be associated with other vaccines; e.g. I.B.R. AND PI3. The basic recom- mendations would be to vaccinate all mature females during the first thirty days after calving, and in problem herds to booster this with a second vaccination during the last two months of age and a second vaccination at 8 to 12 months. In problem herds, heifers should probably be re -vaccinated just prior to breeding. Although B.V.D. has normally been considered a disease of beef cattle it has assumed greater importance in dairy herds over the last five years and is becoming more prevalent in this area of S.W. Ontario. Your local veterinarian can help diagnose the disease from the clinical history of your herd and a clinical examination of your animals. He or she can confirm the disease with blood samples. Not all veterinarians agree with vac- cinating against B.V.D., especially in herds with a history of clinical cases, and his or her advice is the best for your particular herd.